University spin-offs are not just startups; they are powerful engines driving Europe’s deep tech ecosystem. A newly released report, Spin-offs: Reinforcing a Vector of Value Creation for EU-27, delves into the crucial role these ventures play in translating cutting-edge research into market-ready solutions, fostering regional economic development, and propelling technological innovation. Supported by the European Union, this comprehensive study uncovers key trends, challenges, and actionable strategies to maximize the success of these vital companies.